Single-sequence prediction
ESMFold estimates a protein's 3D structure directly from its amino acid sequence.
Protein Structure Predictor
From amino acid sequence to a predicted 3D fold.
Select a disease-related protein or paste a sequence, run it through AlphaGene Fold, and inspect the predicted structure directly in your browser.
01 / Sequence
Enter a protein sequence.
Curated example library
Choose a disease-related protein
48 curated proteins · Human · Dog · Cat
This is a curated, expandable library of commonly studied examples—not an exhaustive list of every disease-associated protein or a diagnostic panel. “Biomarker,” “research target,” and “clinically validated target” are different evidence levels.
02 / Predicted structure
Interactive 3D view
Drag to rotate · Scroll or pinch to zoom · Right-drag to move
Your predicted structure will appear here.
Choose a disease-related protein or enter your own sequence to begin.
Folding sequence…
Estimated progress · Longer sequences can take several minutes.
Sequence length
—
Mean confidence
—
Model
AlphaGene Fold
Confidence
Very high
Confident
Low
Very low
What the predictor does
A fast fold hypothesis—not a finished protein product.
Interactive inspection
Rotate, zoom, and compare cartoon, stick, and surface representations in the browser.
Not protein design
This predictor folds a sequence you provide. It does not generate a new sequence for a function.
Research-use limitation
Predictions do not establish function, binding, safety, efficacy, or an experimentally validated structure.
Beyond prediction